Recombinant Human ITM2B/imBRI2/BRI,BR

产品属性 Product Attributes

基本信息

别名： Integral Membrane Protein 2B;Immature BRI2;imBRI2;Protein E25B;Transmembrane Protein BRI;Bri;ITM2B;BRI;BRI2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface.ITM2B forms homodimer through disulfide-linked interaction with SPPL2A，SPPL2B and APP.ITM2B is expressed in brain and the other tissues.Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2).CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervous system.CAA-ITM2B2 characterized by amyloid deposition in the walls of the blood vessels of the cerebrum，choroid plexus，cerebellum，spinal cord and retina.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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