Recombinant Human VAP-1/SSAO/HPAO/AOC3,BR

产品属性 Product Attributes

基本信息

别名： Membrane primary amine oxidase;Copper amine oxidase;Semicarbazide-sensitive amine oxidase;Vascular adhesion protein 1;AOC3;VAP-1;SSAO;HPAO
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Membrane primary amine oxidase(AOC3)，also known as vascular adhesion protein (VAP-1) and HPAO，this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family.VAP-1 is a type 1 membrane-bound glycoprotein that has a distal adhesion domain and an enzymatically active amine oxidase site outside of the membrane，VAP-1 has adhesive properties，functional monoamine oxidase activity，and possibly plays a role in glucose handling，leukocyte trafficking，and migration during inflammation.This rise in metabolic products contributes to generating advanced glycation end-products and oxidative stress along with the monoamine detoxification in the organism.It is highly expressed on the endothelium of the lung and trachea，and absent from leukocytes and epithelial cells.Membrane-bound VAP-1 releases an active，soluble form of the protein，which may be conducive to increased inflammation and the progression of many vascular disorders.In particular，elevation of VAP-1 activity and the increased enzymatic-mediated deamination is proposed to play a role in renal and vascular disease，oxidative stress，acute and chronic hyperglycemia，and diabetes complications.
来源： Human Cells

其它标识

溶剂: Dissolve the lyophilized protein in distilled water.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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