Recombin human JAB1 protein,BR

产品属性 Product Attributes

基本信息

基因名: JAB1
别名: CSN5，JAB1，MOV-34，SGN5
全名: COP9 constitutive photomorphogenic homolog subunit 5
英文名称: Recombinant human JAB1 protein
中文名称: Jun活化结构域结合蛋白1,COP9信号体复合体亚基5
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Liquid: Supplied as a 0.2 μm filtered solution of 20mM Tris, 0.5M NaCl, 10% Gly, pH8.0.
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at < -70°C for 6 months.Please minimize freeze-thaw cycles.
运输条件: The product is shipped on dry ice.Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q92905
Gene ID： 10987
交叉反应： Human Mouse
分子量： 38kDa
区间范围： 1-334aa
背景说明： The protein encoded by this gene is a member of the STAT protein family.In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2.This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis.The small GTPase Rac1 has been shown to bind and regulate the activity of this protein.PIAS3 protein is a specific inhibitor of this protein.Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome.Alternative splicing results in multiple transcript variants encoding distinct isoforms.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。