Recombin human ZC3HC1 protein,BR

产品属性 Product Attributes

基本信息

基因名: ZC3HC1
别名: HSPC216;NIPA;nuclear-interacting partner of ALK
全名: Nuclear-interacting partner of ALK
英文名称: Recombinant human ZC3HC1 protein
中文名称: ALK的核相互作用伙伴蛋白
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q86WB0
Gene ID： 51530
交叉反应： Human Mouse (Gorilla)
分子量： 23kDa
区间范围： 291-502aa
背景说明： Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1).Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase.Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry.May have an antiapoptotic role in NPM-ALK-mediated signaling events.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

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