Recombin human TPMT protein,BR

产品属性 Product Attributes

基本信息

基因名: TPMT
别名: Thiopurine methyltransferase，thiopurine S methyltransferase，TPMT
全名: thiopurine S-methyltransferase
英文名称: Recombinant human TPMT protein
中文名称: 硫嘌呤甲基转移酶
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： P51580
Gene ID： 7172
交叉反应： Human Mouse Rat (Bovine Zebrafish Cat Dog Horse Gorilla Rabbit Horse Monkey)
分子量： 28kDa
区间范围： 1-245aa
背景说明： This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct.Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents.Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency.Related pseudogenes have been identified on chromosomes 3, 18 and X.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

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