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- Recombin human PSMD2 protein,BR
Recombin human PSMD2 protein,BR
Recombinant human PSMD2 protein
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产品属性 Product Attributes
基本信息
基因名: PSMD2别名: 26S proteasome subunit p97,P97,Protein 55.11,PSMD2,Rpn1,S2,TRAP2
全名: 26S proteasome non-ATPase regulatory subunit 2
英文名称: Recombinant human PSMD2 protein
中文名称: 26S蛋白酶体非ATPase调节亚基2
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.
产品信息
Swiss Prot: Q13200Gene ID: 5708
交叉反应: Human Mouse Rat (Bovine Gorilla)
分子量: 38kDa
区间范围: 559-908aa
背景说明: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator.The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.This gene encodes one of the non-ATPase subunits of the 19S regulator lid.In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor.A pseudogene has been identified on chromosome 1.Alternative splicing results in multiple transcript variants of this gene.
应用: Immunology research
来源: E.coli
其它标识
纯化方法: NI-NTA affinity purification溶剂: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素: Not measured
生物活性: N0
标签信息: With a 6×His tag at the N/C-terminus.
产品介绍 Product Introduction
暂无数据注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。