Recombin human DUSP3 protein,BR

产品属性 Product Attributes

基本信息

基因名: DUSP3
别名: VHR
全名: dual specificity phosphatase 3
英文名称: Recombinant human DUSP3 protein
中文名称: 双特异性蛋白磷酸酶3
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Liquid: Supplied as a 0.2 μm filtered solution of 20mM Tris, 20mM NaCl, 1mM EDTA, 10% Gly, pH8.0.
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at < -70°C for 6 months.Please minimize freeze-thaw cycles.
运输条件: The product is shipped on dry ice.Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： P51452
Gene ID： 1845
交叉反应： Human Mouse Rat (Gorilla)
分子量： 16kDa
区间范围： 1-144aa
背景说明： The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer.Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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