Recombin human GPX1 protein,BR

产品属性 Product Attributes

基本信息

基因名: GPX1
别名: GPX1;GPXD;GSHPX1;glutathione peroxidase 1
全名: glutathione peroxidase 1
英文名称: Recombinant human GPX1 protein
中文名称: 谷胱甘肽过氧化物酶1
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： P07203
Gene ID： 2876
交叉反应： Human Mouse Rat (Bovine Pig Rabbit Chicken)
分子量： 16kDa
区间范围： 59-203aa
背景说明： The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage.Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes.Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity.This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide.It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site.Sec is encoded by the UGA codon, which normally signals translation termination.The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.This gene contains an in-frame GCG trinucleotide repeat in the coding region, and three alleles with 4, 5 or 6 repeats have been found in the human population.The allele with 4 GCG repeats has been significantly associated with breast cancer risk in premenopausal women.Alternatively spliced transcript variants and multiple pseudogenes of this gene have been identified.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

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