Recombin human SFRS1 protein,BR

产品属性 Product Attributes

基本信息

基因名: SFRS1
别名: ASF;SF2;SF2p33;SFRS1;SRp30a
英文名称: Recombinant human SFRS1 protein
全名: splicing factor，arginine/serine-rich 1
中文名称: 剪接因子,精氨酸/丝氨酸丰富1
规格: 1mg ; 100ug ; 50ug ; 10ug
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q07955
Gene ID： 6426
交叉反应： Human Mouse (Bovine Pig Gorilla Chicken)
分子量： 28kDa
区间范围： 1-248aa
背景说明： Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing.Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF.Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA.Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC.Binds preferentially to the 5'-CGAGGCG-3' motif in vitro.Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing.Isoform ASF-2 and isoform ASF-3 act as splicing repressors.May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

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