Recombin human SIX1 protein,BR

产品属性 Product Attributes

基本信息

基因名: SIX1
别名: BOS3;DFNA23;TIP39
英文名称: Recombinant human SIX1 protein
全名: Homeobox protein SIX1
中文名称: 同源盒蛋白SIX1
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q15475
Gene ID： 6495
交叉反应： Human Mouse
分子量： 32kDa
区间范围： 1-284aa
背景说明： Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development.Plays an important role in the development of several organs, including kidney, muscle and inner ear.Depending on context, functions as transcriptional repressor or activator.Lacks an activation domain, and requires interaction with EYA family members for transcription activation.Mediates nuclear translocation of EYA1 and EYA2.Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter.Regulates the expression of numerous genes, including MYC, CCND1 and EZR.Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2.Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex.During myogenesis, seems to act together with EYA2 and DACH2.Regulates the expression of CCNA1.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。