Recombin human KLHL12 protein,BR

产品属性 Product Attributes

基本信息

基因名: KLHL12
别名: C3IP1
英文名称: Recombinant human KLHL12 protein
全名: Kelch-like protein 12
中文名称: Kelch样蛋白12
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q53G59
Gene ID： 59349
交叉反应： Human Mouse Rat (Bovine Zebrafish)
分子量： 38kDa
区间范围： 219-568aa
背景说明： This gene encodes a member of the KLHL (Kelch-like) family of proteins.This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis.This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation.Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size.A pseudogene has been identified on chromosome 22.Alternative splicing results in multiple transcript variants.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

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