Recombin human WAC protein,BR

产品属性 Product Attributes

基本信息

基因名: WAC
别名: BM-016;FLJ31290;MGC10753;PRO1741;Wwp4
英文名称: Recombinant human WAC protein
全名: WW domain containing adaptor with coiled-coil
中文名称: WW结构域包含带螺旋线圈的适配蛋白
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q9BTA9
Gene ID： 51322
交叉反应： Human Mouse
分子量： 23kDa
区间范围： 1-210aa
背景说明： Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1) ref.Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription ref.Regulates the cell-cycle checkpoint activation in response to DNA damage ref.Positive regulator of amino acid starvation-induced autophagy ref.Also acts as a negative regulator of basal autophagy ref.Positively regulates MTOR activity by promoting, in an energy-dependent manner, the assembly of the TTT complex composed of TELO2, TTI1 and TTI2 and the RUVBL complex composed of RUVBL1 and RUVBL2 into the TTT-RUVBL complex.This leads to the dimerization of the mTORC1 complex and its subsequent activation ref.May negatively regulate the ubiquitin proteasome pathway ref.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

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