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- Recombin human PSME3 protein,BR
Recombin human PSME3 protein,BR
Recombinant human PSME3 protein
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产品属性 Product Attributes
基本信息
基因名: PSME3别名: PSME3;HEL-S-283;Ki;PA28-gamma;PA28G;PA28gamma;REG-GAMMA
英文名称: Recombinant human PSME3 protein
全名: proteasome (prosome,macropain) activator subunit 3 (PA28 gamma;Ki)
中文名称: 蛋白酶体激活剂亚基3
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.
产品信息
Swiss Prot: P61289Gene ID: 10197
交叉反应: Human Mouse (Pig Chicken Gorilla)
分子量: 28kDa
区间范围: 1-255aa
背景说明: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator.The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator.Three subunits (alpha, beta and gamma) of the 11S regulator have been identified.This gene encodes the gamma subunit of the 11S regulator.Six gamma subunits combine to form a homohexameric ring.Alternate splicing results in multiple transcript variants.
应用: Immunology research
来源: E.coli
其它标识
纯化方法: NI-NTA affinity purification溶剂: Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素: Not measured
生物活性: N0
标签信息: With a 6×His tag at the N/C-terminus.
产品介绍 Product Introduction
暂无数据注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。