Recombinant human MARK3 protein,BR

产品属性 Product Attributes

基本信息

基因名： MARK3
别名： C-TAK1;Cdc25C associated protein kinase 1;Cdc25C-associated protein kinase 1;cTAK1;ELKL motif kinase 2;EMK-2;Emk2;ETK 1;KIAA4230;KP78;MAP microtubule affinity regulating kinase 3;MAP/microtubule affinity-regulating kinase 3;Mark3;MARK3_HUMAN;Par 1a;PAR1A;Protein kinase STK10;Ser/Thr protein kinase PAR-1;Serine threonine protein kinase p78;Serine/threonine-protein kinase p78;SerThr protein kinase PAR 1;
英文名称： Recombinant Human MARK3 Protein
全名： MAP/microtubule affinity-regulating kinase 3
中文名称： 微管亲和调控蛋白激酶3
规格： 10ug ; 50ug ; 100ug ; 1mg
外观(性状)： Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度： ≥85% by SDS-PAGE.
储存条件： Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件： 冷藏运输
浓度： 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： P27448
Gene ID： 4140
交叉反应： Human Mouse Rat
分子量： 39kDa
区间范围： 42-392aa
背景说明： Serine/threonine-protein kinase (PubMed:23666762).Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4.Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762).Phosphorylates CDC25C on 'Ser-216'.Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613).Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1.Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714).
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： NO
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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