Recombin human USP18 protein,BR

产品属性 Product Attributes

基本信息

基因名: USP18
别名: 43 kDa ISG15 specific protease;43 kDa ISG15-specific protease;EC 3.1.2.;hUBP43;Interferon Stimulated Gene 43 kD;ISG15 Specific Processing Protease;ISG15-specific-processing protease;ISG43;Ubiquitin Specific Peptidase 18;Ubiquitin Specific Protease 18 43 kD;Ubiquitin Specific Protease 18;Ubl carboxyl terminal hydrolase 18;Ubl carboxyl-terminal hydrolase 18;Ubl thioesterase 18;Ubl thiolesterase 18;Ubp15;UBP18_HUMAN;USP18;
英文名称: Recombinant human USP18 protein
全名: ubiquitin specific peptidase 18
中文名称: 泛素特异性肽酶18
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q9UMW8
Gene ID： 11274
交叉反应： Human Mouse (Gorilla)
分子量： 41kDa
区间范围： 1-372aa
背景说明： The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates.It is highly expressed in liver and thymus, and is localized to the nucleus.This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease.Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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