Recombin human EIF3I protein,BR

产品属性 Product Attributes

基本信息

基因名: EIF3I
别名: eIF-3-beta;eIF3 beta;eIF3 p36;eIF3-beta;eIF3-p36;eIF3i;EIF3I_HUMAN;EIF3S2;EIF3S2，formerly;Eukaryotic translation initiation factor 3 subunit 2;Eukaryotic translation initiation factor 3 subunit 2 beta;Eukaryotic translation initiation factor 3 subunit I;eukaryotic translation initiation factor 3，subunit 2 (beta，36kD;eukaryotic translation initiation factor 3，subunit 2 beta，36kDa;eukaryotic translation initiation factor 3，subunit 2，formerly;eukaryotic translation initiation factor 3，subunit I;Predicted protein of HQ2242;PRO2242;TGF beta receptor interacting protein 1;TGF-beta receptor-interacting protein 1;TGFbeta receptor interacting protein 1;TGFbeta receptor-interacting protein 1;TRIP 1;TRIP-1;TRIP1;
英文名称: Recombinant human EIF3I protein
全名: eukaryotic translation initiation factor 3，subunit I
中文名称: 真核翻译起始因子亚单位I
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： Q13347
Gene ID： 8668
交叉反应： Human Mouse Rat (Bovine Gorilla)
分子量： 36kDa
区间范围： 1-326aa
背景说明： Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815).The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632).The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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