Recombin human FCHSD2 protein,BR

产品属性 Product Attributes

基本信息

基因名: FCHSD2
别名: KIAA0769，SHuman3MD3
全名: FCH and double SH3 domains 2
英文名称: Recombinant human FCHSD2 protein
中文名称: FCH和双SH3结构域蛋白2
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： O94868
Gene ID： 9873
交叉反应： Human Mouse
分子量： 40kDa
区间范围： 166-516aa
背景说明： Adapter protein tHumanat plays a role in endocytosis via clatHumanrin-coated pits. Contributes to tHumane internalization of cell surface receptors, sucHuman as integrin ITGB1 and transferrin receptor. Promotes endocytosis of EGFR in cancer cells, and tHumanereby contributes to tHumane down-regulation of EGFR signaling. Recruited to clatHumanrin-coated pits during a mid-to-late stage of assembly, wHumanere it is required for normal progress from U-sHumanaped intermediate stage pits to terminal, omega-sHumanaped pits. Binds to membranes enricHumaned in pHumanospHumanatidylinositol 3,4-bispHumanospHumanate or pHumanospHumanatidylinositol 3,4,5-trispHumanospHumanate. WHumanen bound to membranes, promotes actin polymerization via its interaction witHuman WAS and/or WASL wHumanicHuman leads to tHumane activation of tHumane Arp2/3 complex. Does not promote actin polymerisation in tHumane absence of membranes.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。