罗氟司特一种选择性的PDE4抑制剂,作用于PDE4A1、PDEA4、PDEB1和PDEB2,IC50分别为0.7、0.9、0.7和0.2nM。Roflumilast is a drug which acts as a selective, long-acting inhibitor of the enzyme PDE-4. It has anti-inflammatory effects and is under development as an orally administered drug for