108605-62-5
2-氰基-3-羟基-N-(4-三氟甲基苯基)巴豆酰胺
Teriflunomide(Random Configuration)(订货以英文名为准)| C11840 | CAS:108605-62-5 | 2-氰基-3-羟基-N-(4-(三氟甲基)苯基)丁-2-烯酰胺, 99%, Acmec | 价格库存 收藏产品 | |
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中文名称：
2-氰基-3-羟基-N-(4-三氟甲基苯基)巴豆酰胺
英文名称：
Teriflunomide(Random Configuration)
CAS No.：
108605-62-5
分子式：
C₁₂H₉F₃N₂O₂
分子量：
270.21
InChIKey：
UTNUDOFZCWSZMS-YFHOEESVSA-N
InChI：
InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
Pubchem ID：
GHS符号：
信号词：
Warning
危害声明：
H302
警示性声明：
P280-P305+P351+P338
技术问答
游客JZ2106309300
2021-06-30 13:00
问 特立氟胺用途是什么？
描述：特立氟胺是做什么用的?哪里可以用到特立氟胺?
答
特立氟胺用途Teriflunomide, aslo known as A77 1726, is the active metabolite of leflunomide. Teriflunomide is an immunomodulatory drug inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase. It is uncertain whether this explains its effect on MS lesions. Teriflunomide inhibits rapidly dividing cells, including activated T cells, which are thought to drive the disease process in MS. It has been found that teriflunomide blocks the transcription factor NF-κB. The drug was approved by the FDA on September 13, 2012.
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Tags：108605-62-5,2-氰基-3-羟基-N-(4-三氟甲基苯基)巴豆酰胺,cas号:108605-62-5,cas:108605-62-5
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