Recombinant Human TNFSF10/TRAIL/APO-2L,BR

产品属性 Product Attributes

基本信息

别名： Tumor Necrosis Factor Ligand Superfamily Member 10;Apo-2 Ligand;Apo-2L;TNF-Related Apoptosis-Inducing Ligand;Protein TRAIL;CD253;TNFSF10;APO2L;TRAIL
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 40mM Tris-HCl, 300mM NaCl, 5%Trehalose, 5%Mannitol, 0.01%Tween80, 10%Glycerol, pH7.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输条件： The product is shipped on dry ice/polar packs.

产品信息

背景说明： Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus.TNFSF10 can interact with several distinct receptors.Two of these receptors that belongs to TNFR superfamily，DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2)，are plasma membrane proteins containing intracellular death domains essential for activating apoptosis.TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells，but not in normal cells.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

产品介绍 Product Introduction

Recombinant Human TNF-Related Apoptosis-Inducing Ligand is produced by our E.coli expression system and the target gene encoding Arg115-Gly281 is expressed.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。