Recombinant Human Serpin E1,BR

产品属性 Product Attributes

基本信息

别名： Plasminogen Activator Inhibitor 1;PAI;PAI-1;Endothelial Plasminogen Activator Inhibitor;Serpin E1;SERPINE1;PAI1;PLANH1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： The product is shipped at ambient temperature.

产品信息

背景说明： Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases.They are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation，complement activation，fibrinolysis，angiogenesis，inflammation and tumor suppression and are expressed in a cell-specific manner.Serpin E1 is a secreted protein which belongs to the Serpin family.Serpin E1 acts as 'bait' for tissue plasminogen activator，urokinase，and protein C.Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis.Defects in SERPINE1 are characterized by abnormal bleeding due to Serpin E1 defect in the plasma.High concentrations of Serpin E1 have been associated with thrombophilia which is an autosomal dominant disorder in which affected individuals are prone to develop serious spontaneous thrombosis.
来源： Human cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

产品介绍 Product Introduction

Recombinant Human Serine Protease Inhibitor-clade E1 is produced by our Mammalian expression system and the target gene encoding Val24-Pro402 is expressed with a 6His tag at the C-terminus.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。