Recombinant Human HE4/WFDC2,BR

产品属性 Product Attributes

基本信息

别名： WAP Four-Disulfide Core Domain Protein 2;Epididymal Secretory Protein E4;Major Epididymis-Specific Protein E4;Putative Protease Inhibitor WAP5;WFDC2;HE4;WAP5
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件： The product is shipped at ambient temperature.

产品信息

背景说明： WAP Four-Disulfide Core Domain Protein 2 (WFDC2) is a 25 kDa secreted glycoprotein containing two WAP domains.Mature human WFDC2 is 94 amino acids (aa) in length.It contains two WAP domains that likely mediate antiprotease and/or antimicrobial activity (aa 31 - 73 and 74 - 123).There are four potential splice variants.One shows a deletion of aa 27-74，while three others show aa substitutions: 28 aa for aa 75-124，23 aa for aa 1 - 74，and 10 aa for aa 71-124.WFDC2 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels.It is expressed by a wide variety of epithelial cells，including respiratory epithelium，salivary gland mucous cells，breast duct epithelium，distal tubule renal epithelium，and epididymal epithelium.WFDC2 may be a component of the innate immune defences of the lung，nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence.WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail.Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy，reduced in early lactation and absent in mid-late lactation.WFDC2 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.
来源： Human cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test.

产品介绍 Product Introduction

Recombinant Human WAP Four-Disulfide Core Domain Protein 2 is produced by our Mammalian expression system and the target gene encoding Glu31-Phe124 is expressed with a 6His tag at the C-terminus.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。