Recombinant Human R-spondin-1/RSPO1,BR

产品属性 Product Attributes

基本信息

别名： RSPO1;R-spondin1;RP11-566C13.1;CRISTIN3;FLJ40906;RSPO Rspo1;R-spondin;Rspondin;RP23-325M14.2;Roof plate-specific spondin-1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months.
运输条件： The product is shipped at ambient temperature.Upon receipt，store it immediately at the temperature listed below.

产品信息

背景说明： RSPO1 is a secreted protein，containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family.RSPO1 is required for the early development of gonads，regardless of sex.It has been found in mice only eleven days after fertilization.To induce cell proliferation，it acts synergistically with WNT4.They help stabilize β catenin，which activates downstream targets.RSPO1 is necessary in female sex development.It augments the WNT/β catenin pathway to oppose male sex development.In critical gonadal stages，between six and nine weeks after fertilization，the ovaries upregulate it while the testes downregulate it.RSPO1 can potentially aid in the treatment of mucositis，which is characterized by inflammation of the oral cavity.This unfortunate condition often accompanies chemotherapy and radiation in cancer patients with head and neck tumors.
来源： Human cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

Recombinant Human R-spondin-1 is produced by our Mammalian expression system and the target gene encoding Arg31-Ala263 is expressed with a 6His tag at the C-terminus.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。