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- Recombinant Human Fibroblast growth factor 10/FGF10,BR
Recombinant Human Fibroblast growth factor 10/FGF10,BR
Recombinant Human Fibroblast growth factor 10/FGF10
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产品属性 Product Attributes
基本信息
别名: Fibroblast growth factor 10;FGF-10;Keratinocyte growth factor 2;FGF10;KGF-2;KGF2规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状): Lyophilized from a 0.2 μm filtered solution of 20mM Tris,200mM NaCl,pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件: The product is shipped at ambient temperature.Upon receipt,store it immediately at the temperature listed below.
产品信息
背景说明: Fibroblast growth factor 10 (FGF-10,KGF-2),is a member of the fibroblast growth factor (FGF) family that includes FGF-3,-7,and -22.KGF-2 is secreted by mesenchymal cells and associates with extracellular FGF-BP.It preferentially binds and activates epithelial cell FGFR2 and interacts more weakly with FGFR1.It plays an important role in the regulation of embryonic development,cell proliferation and cell differentiation.It exhibits mitogenic activity for keratinizing epidermal cells,but essentially no activity for fibroblasts,which is similar to the biological activity of FGF7.FGF10 is required for normal branching morphogenesis.Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands (ALSG).ALSG has variable expressivity,and affected individuals may have aplasia or hypoplasia of the lacrimal,parotid,submandibular and sublingual glands and absence of the lacrimal puncta.The disorder is characterized by irritable eyes,recurrent eye infections,epiphora (constant tearing) and xerostomia (dryness of the mouth),which increases the risk of dental erosion,dental caries,periodontal disease and oral infections.来源: E.coli
其它标识
溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
产品介绍 Product Introduction
Recombinant Human Fibroblast Growth Factor 10 is produced by our E.coli expression system and the target gene encoding Gln38-Ser208 is expressed.注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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