人激肽释放酶15检测试剂盒,BR

产品属性 Product Attributes

基本信息

中文名称： 人激肽释放酶15检测试剂盒
英文名称： Human Kallikrein 15 ELISA Kit
别名： ACO protease; ACO; HSRNASPH; Kallikrein 15; kallikrein-15; kallikrein-like serine protease; kallikrein-related peptidase 15; KLK15; Prostinogen
储存条件： 2-8℃，6 months
规格： 96T ; 48T
检测目标： Kallikrein 15
样品类型： 血清/血浆/细胞培养上清
反应性： Human
应用： ELISA
定量/定性： 定量检测
检测范围： 78.125-5000pg/mL
灵敏度： 39pg/mL
精密度： 板内，板间变异系数均<10%
回收率： 80%-120%

Elisa信息

Swiss Prot： Q9H2R5
Gene ID： 55554
背景说明： The human tissue kallikrein (KLK) gene family contains 15 members that play important roles in cancer. Notably, kallikrein-1, also known as tissue kallikrein, cleaves kininogen to release the vasoactive kinin peptide, bradykinin or lysyl-bradykinin. Kallikrein-3, called prostate specific antigen (PSA), is an established tumor marker that aids in the diagnosis, staging, and follow up of prostate cancer. Kallikrein-4 is specifically expressed in the prostate and over-expressed in prostate cancer. Kallikrein-5 is widely expressed but found at high levels in skin, breast, brain and testis; over-expression is an indicator of poor prognosis in ovarian cancer. Kallikrein-8 is expressed in the brain and is a novel marker of ovarian and cervical cancer.Human plasma kallikrein, a serine protease, is synthesized in the liver and circulates in the plasma bound to high molecular weight (HMW) kininogen or as a free zymogen. Once activated by its physiological activator, coagulation factor XII, it displays endopeptidase activity towards peptide bonds after arginine (preferred) and lysine. It cleaves HMW kininogen, its major physiological substrate, to release the potent vasodilator peptide bradykinin. It is also able to cleave a number of inactive precursor proteins to generate active products, such as plasminogen and prourokinase.

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。