猪胰岛素样生长因子结合蛋白4检测试剂盒,BR

产品属性 Product Attributes

基本信息

中文名称： 猪胰岛素样生长因子结合蛋白4检测试剂盒
英文名称： Porcine IGFBP-4 ELISA Kit
别名： BP-4; HT29-IGFBP; IBP4; IGF-binding protein 4; IGFBP4; IGFBP-4; IGFBP-4IBP-4; Insulin-Like Growth Factor Binding Protein 4
储存条件： 2-8℃，6 months
规格： 48T ; 96T
检测目标： IGFBP-4
样品类型： 血清/血浆/细胞培养上清
反应性： Porcine
应用： ELISA
定量/定性： 定量检测
检测范围： 62-4000pg/mL
灵敏度： 13pg/mL
精密度： 板内，板间变异系数均<10%
回收率： 80%-120%
反应时间： 3h15min

Elisa信息

Swiss Prot： P24854
Gene ID： 100144490
背景说明： The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.

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