Anti-GSDMD Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称：Anti-GSDMD Polyclonal Antibody

中文名称：Gasdermin D蛋白抗体

规格：50ul ; 100ul

宿主：Rabbit

克隆类型：Polyclonal Antibody

亚型：IgG

交叉反应：Human ; Rat ; Mouse

应用：WB ; IHC ; IF/ICC ; IP ; FCM ; ELISA

稀释比例：WB 1:2000-10000. IHC 1:50-500. IF/ICC 1:50-500. IP 0.5-4.0ug for 1.0-3.0mg extracts. FCM 1×10^6 cells+0.40ug.

抗体信息

靶标：GSDMD

别名：DF5L, DFNA5L, FKSG10, gasdermin D, GSDMD, GSDMDC1

背景说明

GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Swiss Prot：P57764

Gene ID：79792

亚细胞定位：Cytoplasmic membrane extracellular matrix secreted

研究领域：免疫学 ; 细胞生物学

免疫原：Recombinant protein of human GSDMD

Public Immunogen Range：135-484aa

理论分子量：53kDa

实际分子量：53kDa

其它标识

纯化方法：Affinity purification

储存液：PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

储存条件：Store at -20℃. Avoid freeze / thaw cycles.

运输条件：冷冻运输

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。