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Anti-IKZF1 Monoclonal Antibody,BR
Anti-IKZF1 Monoclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-IKZF1 Monoclonal Antibody中文名称: 锌指蛋白IKAROS抗体
规格: 100ul ; 50ul
宿主: Mouse
克隆类型: Monoclonal Antibody
亚型: IgG1克隆号 1A12-F2-D8
交叉反应:: Human
应用: IP ; WB
稀释比例: WB 1:500-1000. IP 1:20.
抗体信息
靶标: IKZF1别名: CVID13;Hs.54452;IK1;IKAROS;LyF-1;LYF1;PPP1R92;PRO0758;ZNFN1A1
背景说明: Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs).
Swiss Prot: Q13422
Gene ID: 10320
亚细胞定位: Cytoplasm Nucleus Nucleus
免疫原: Recombinant protein of human IKZF1
理论分子量: 58kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,0.5% BSA,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze / thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。