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- Anti-PARP Monoclonal Antibody,BR
Anti-PARP Monoclonal Antibody,BR
Anti-PARP Monoclonal Antibody
(订货以英文名为准)猜你喜欢
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宿主:Mouse
别名:ADPRT;ADPRT1;ADPRT1;ARTD1;pADPRT-1;PARP;PARP-1;PPOL
交叉反应:Human
应用:WB IHC
稀释比例:WB 1:1000-3000. IHC 1:200-500.
蛋白分子量:116/89kDa
Gene ID:142
保存:Store at -20°C. Avoid freeze / thaw cycles.
储存液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Saturated ammonium sulfate precipitation
亚型:IgG1
免疫原:Synthetic Peptide
性状:液体
亚细胞定位:Nucleus nucleolus
Swiss Prot:P09874
克隆号:M3
背景资料:Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.
Public Immunogen Range:Synthetic Peptide
克隆类型:Monoclonal Antibody
规格:50ul, 100ul, 注意:
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。