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- Anti-SFPQ Polyclonal Antibody,BR
Anti-SFPQ Polyclonal Antibody,BR
Anti-SFPQ Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-SFPQ Polyclonal Antibody中文名称: 多聚嘧啶序列结合蛋白相关剪接因子PSF抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Human ; Rat
应用: IP ; IF ; IHC ; WB
稀释比例: WB 1:500-1000. IHC 1:50-200. IF 1:50-100. IP 0.5μg-4μg.
抗体信息
靶标: SFPQ别名: 100 kDa DNA pairing protein,hPOMp100,POMP100,PSF,PTB associated splicing factor,SFPQ
背景说明: SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer's disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD.
Swiss Prot: P23246
Gene ID: 6421
亚细胞定位: Cytoplasm Nucleus matrix
免疫原: Recombinant protein of human SFPQ
Public Immunogen Range: 578-707aa
理论分子量: 76kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。