Anti-SFPQ Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-SFPQ Polyclonal Antibody
中文名称： 多聚嘧啶序列结合蛋白相关剪接因子PSF抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human ; Rat
应用： IP ; IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-100. IP 0.5μg-4μg.

抗体信息

靶标： SFPQ
别名： 100 kDa DNA pairing protein,hPOMp100,POMP100,PSF,PTB associated splicing factor,SFPQ
背景说明： SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer's disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD.
Swiss Prot： P23246
Gene ID： 6421
亚细胞定位： Cytoplasm Nucleus matrix
免疫原： Recombinant protein of human SFPQ
Public Immunogen Range： 578-707aa
理论分子量： 76kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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