Anti-PCBP2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PCBP2 Polyclonal Antibody
中文名称： 异构核糖核蛋白E2抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Human ; Rat
应用： IF ; IHC ; WB
稀释比例： WB 1:500-1000.IHC 1:50-200.IF 1:50-200.

抗体信息

靶标： PCBP2
别名： Alpha CP2, Alpha-CP2, alphaCP-2, Cbp, CTBP, Heterogeneous nuclear ribonucleoprotein E2, Heterogenous nuclear ribonucleoprotein E2, hnRNP E2, hnRNP-E2, HNRNPE2, Hnrnpx, HNRPE2, Hnrpx, MGC110998, PCBP2, PCBP2_HUMAN, poly(rC) binding protein 2, Poly(rC)-binding protein 2, Putative heterogeneous nuclear ribonucleoprotein X, rCbinding protein 2
背景说明： The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q15366
Gene ID： 5094
亚细胞定位： Cytoplasm Nucleus
免疫原： A synthetic peptide of human PCBP2
Public Immunogen Range： 150-250aa
理论分子量： 39kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。