Anti-HSPA5(C-term) Monoclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-HSPA5(C-term) Monoclonal Antibody
中文名称： 葡萄糖调节蛋白78/热休克蛋白70蛋白5抗体
规格： 100ul ; 50ul
宿主： Mouse
克隆类型： Monoclonal Antibody
亚型： IgG1克隆号 9E4-2A7-H6
交叉反应：： Rat ; Human
应用： ICC ; IF ; IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-100. IF 1:50-200. ICC 1:50-200.

抗体信息

靶标： HSPA5(C-term)
别名： BIP, HSPA5, GRP-78, glucose regulated protein 78, 78 kDa glucose regulated protein, BIP, Endoplasmic reticulum lumenal Ca2+ binding protein grp78, FLJ26106, Glucose Regulated Protein 78kDa, GRP 78, Heat Shock 70kDa Protein 5, HSPA 5, HSPA-5, Immunoglobulin Heavy Chain Binding Protein, MIF2, GRP78_HUMAN
背景说明： The 78 kDa glucose regulated protein/BiP (GRP78) belongs to the family of ~70 kDa heat shock proteins (HSP 70). GRP78 is a resident protein of the endoplasmic reticulum (ER) and may associate transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins that are incorrectly folded, thus preventing their export from the ER lumen. GRP78 is a highly conserved protein that is essential for cell viability. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP 94) and protein disulfide isomerase (PDI). The presence of carboxy terminal KDEL appears to be necessary for retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
Swiss Prot： P11021
Gene ID： 3309
亚细胞定位： Cytoplasm Endoplasmic reticulum lumen Melanosome
免疫原： Recombinant protein of human HSPA5(C-term)
理论分子量： 72kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze / thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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