Anti-NOTCH3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NOTCH3 Polyclonal Antibody
中文名称： 跨膜受体蛋白Notch-3抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat
应用： IF ; WB
稀释比例： WB 1:500-2000.IF 1:50-200

抗体信息

靶标： NOTCH3
别名： CADASIL, CASIL, NOTC3_HUMAN, Notch 3, Notch 3 intracellular domain, Notch homolog 3, Notch3
背景说明： This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Swiss Prot： Q9UM47
Gene ID： 4854
亚细胞定位： Cell membrane Nucleus Single-pass type I membrane protein
免疫原： Recombinant Protein of human NOTCH3
Public Immunogen Range： 751-850aa
理论分子量： 244kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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