Anti-ROCK1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ROCK1 Polyclonal Antibody
中文名称： Rho相关蛋白激酶1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse
应用： IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-100.

抗体信息

靶标： ROCK1
别名： p160 ROCK1, p160ROCK, Renal carcinoma antigen NY REN 35, Rho associated coiled coil containing protein kinase 1, Rho associated protein kinase 1, Rho-associated coiled-coil containing protein kinase 1, ROCK1_HUMAN
背景说明： This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.
Swiss Prot： Q13464
Gene ID： 6093
亚细胞定位： Cell membrane Cell projection Cytoplasm Golgi apparatus membrane Peripheral membrane protein bleb centriole centrosome cytoskeleton lamellipodium microtubule organizing center ruffle
免疫原： Recombinant protein of human ROCK1
Public Immunogen Range： 400-660aa
理论分子量： 158kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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