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Anti-TYMS Polyclonal Antibody,BR
Anti-TYMS Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-TYMS Polyclonal Antibody中文名称: 胸苷酸合成酶抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Human
应用: IHC ; WB
稀释比例: WB 1:500-1000. IHC 1:50-200.
抗体信息
靶标: TYMS别名: d TMP synthase, EC 2.1.1.45, HsT422, MGC88736, Thymidylate synthase, thymidylate synthetase, TMS, TS, TSase, TYMS, TYMS protein, Tyms thymidylate synthetase, TYSY_HUMAN
背景说明: Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.
Swiss Prot: P04818
Gene ID: 7298
亚细胞定位: Cytoplasm Mitochondrion Mitochondrion inner membrane Mitochondrion matrix Nucleus
免疫原: Recombinant protein of human TYMS
Public Immunogen Range: 1-313aa
理论分子量: 36kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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