Anti-CTNNB1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CTNNB1 Polyclonal Antibody
中文名称： β-连环蛋白/β-连环素/β链接素抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Rat ; Mouse
应用： WB
稀释比例： WB 1:500-2000.

抗体信息

靶标： CTNNB1
别名： CTNNB;MRD19;armadillo;β-Catenin;Cadherin associated protein
背景说明： The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.
Swiss Prot： P35222
Gene ID： 1499
亚细胞定位： Cell junction Cell membrane Cytoplasm Nucleus adherens junction centrosome cytoskeleton microtubule organizing center spindle pole
免疫原： A synthetic peptide of human CTNNB1
Public Immunogen Range： 650-750aa
理论分子量： 85kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。