Anti-PML Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PML Polyclonal Antibody
中文名称： 早幼粒细胞白血病蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IHC ; WB
稀释比例： WB 1:500-2000.IHC 1:50-200

抗体信息

靶标： PML
别名： PML Protein, MYL, PML, PML_HUMAN, PP8675, Probable transcription factor PML, Promyelocytic leukemia, Promyelocytic leukemia inducer of, Promyelocytic leukemia protein, Protein PML, RING finger protein 71, RNF 71, RNF71, TRIM 19, TRIM19, Tripartite motif containing protein 19, Tripartite motif protein TRIM19, Tripartite motif-containing protein 19
背景说明： The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified.
Swiss Prot： P29590
Gene ID： 5371
亚细胞定位： Cytoplasm Cytoplasmic side Early endosome membrane Endoplasmic reticulum membrane Nucleus PML body Peripheral membrane protein nucleolus nucleoplasm
免疫原： Recombinant protein of human PML
Public Immunogen Range： 300-600aa
理论分子量： 98kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。