Anti-CLDN11 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CLDN11 Polyclonal Antibody
中文名称： 少突胶质细胞跨膜蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Mouse ; Rat ; Human
应用： IHC ; WB
稀释比例： WB 1:500-1000. IHC 1:50-100.

抗体信息

靶标： CLDN11
别名： CLD11_MOUSE, CLD11_HUMAN, Oligodendrocyte Specific Protein, Oligodendrocyte transmembrane protein, Claudin 11, claudin11, claudin-11, CLDN 11, OSP, OTM
背景说明： This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.
Swiss Prot： O75508
Gene ID： 5010
亚细胞定位： Cell junction Cell membrane Multi-pass membrane protein tight junction
免疫原： A synthetic peptide of human CLDN11
Public Immunogen Range： 1-100aa
理论分子量： 22kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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