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Anti-TLR3 Polyclonal Antibody,BR
Anti-TLR3 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-TLR3 Polyclonal Antibody中文名称: Toll样受体3抗体
规格: 50ul ; 100ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Human
应用: WB
稀释比例: WB 1:500-2000. IHC 1:50-200.
抗体信息
靶标: TLR3别名: Toll-like receptor 3, TLR3, CD283, CD283 antigen, TLR 3, Toll Like Receptor 3, TLR3_HUMAN
背景说明: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
Swiss Prot: O15455
Gene ID: 7098
亚细胞定位: Cytoplasm Early endosome Endoplasmic reticulum membrane Endosome membrane Single-pass type I membrane protein
免疫原: Recombinant protein of human TLR3
理论分子量: 72/103kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.03% Proclin300,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。