Anti-CD209 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-CD209 Polyclonal Antibody
中文名称： 细胞间粘附分子非整合素蛋白3抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： IF ; WB
稀释比例： WB 1:500-1000. IF 1:50-200.

抗体信息

靶标： CD209
别名： CLEC4L, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, C type lectin domain family 4 member L, CD 209, CD209, CD209 antigen, CD209 antigen-like protein A, CD209 molecule, Cd209a, CDSIGN, CIRE, DC SIGN1, DCSIGN, Dendritic cell specific ICAM 3 grabbing nonintegrin 1, Dendritic cell specific ICAM3 grabbing nonintegrin 1, Dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin, Dengue fever, protection against, included, Dentritic Cell Specific ICAM3 Grabbing Nonintegrin, HIV GP120 Binding Protein, MGC129965, MGC130443, SIGN-R1, SIGNR5, CD209_HUMAN
背景说明： This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332; often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.
Swiss Prot： Q9NNX6
Gene ID： 30835
亚细胞定位： Cell membrane Secreted Single-pass type II membrane protein
免疫原： Recombinant protein of human CD209
Public Immunogen Range： 265-404aa
理论分子量： 46kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。