Anti-HLA-DRA Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-HLA-DRA Polyclonal Antibody
中文名称： 主要组织相容性复合体II类DRα抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： WB
稀释比例： WB 1:500-2000

抗体信息

靶标： HLA-DRA
别名： CD, CELIAC 1, CELIAC1, DP beta 1 chain, DP(W4) beta chain, DPB1, DPB1_HUMAN, DQ A1, DRB1, DRB4, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, HLA class II histocompatibility antigen DR 1 beta, HLA class II histocompatibility antigen DR alpha, HLA class II histocompatibility antigen DR alpha chain, HLA DP histocompatibility type beta 1 subunit, HLA DP1B, HLA DPB1, HLA DQA, HLA DQA1, HLA DQB, HLA DQB1, HLA DR1B, HLA DR3B, HLA DR4B, HLA DRA, HLA DRA1, HLA DRB1, HLA DRB3, HLA DRB4, HLA DRB5, HLA-DPB1, IDDM 1, IDDM1, Major histocompatibility complex class II DP beta 1, Major histocompatibility complex class II DQ alpha 1, Major histocompatibility complex class II DQ beta 1, Major histocompatibility complex class II DR alpha, Major histocompatibility complex class II DR beta 1, Major histocompatibility complex class II DR beta 3, Major histocompatibility complex class II DR beta 4, Major histocompatibility complex class II DR beta 5, MGC117330, MHC class II antigen DPB1, MHC class II antigen DRA, MHC class II HLA DQ alpha 1, MHC class II HLA DR beta 1, MHC class II HLA DR beta 3, MHC DPB1, MHC DQ beta, MHC HLA DPB1, MHC HLA DQ alpha
背景说明： HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
Swiss Prot： P01903
Gene ID： 3122
亚细胞定位： Cell membrane Endoplasmic reticulum membrane Endosome membrane Golgi apparatus Late endosome membrane Lysosome membrane Single-pass type I membrane protein trans-Golgi network membrane
免疫原： Recombinant protein of human HLA-DRA
Public Immunogen Range： 26-216aa
理论分子量： 29kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。