Anti-NR0B2 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NR0B2 Polyclonal Antibody
中文名称： 核受体亚家族0,B组成员2抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： WB
稀释比例： WB 1:100-500.

抗体信息

靶标： NR0B2
别名： NR0B2, NR0B2_HUMAN, Nr0b2a, Nuclear receptor subfamily 0 group B member 2, Nuclear receptor subfamily 0, group B, member 2a, Orphan nuclear receptor SHP, SHP, SHP-1, Shp1, Small heterodimer partner
背景说明： The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function.
Swiss Prot： Q15466
Gene ID： 8431
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human NR0B2
Public Immunogen Range： 40-124aa
理论分子量： 28kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。