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Anti-PSMC3 Polyclonal Antibody,BR
Anti-PSMC3 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-PSMC3 Polyclonal Antibody中文名称: 蛋白酶体26S亚基ATP酶3抗体
规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Rat ; Human
应用: IHC ; WB
稀释比例: WB 1:500-2000.IHC 1:50-200
抗体信息
靶标: PSMC3别名: 26S protease regulatory subunit 6A, 26S proteasome AAA-ATPase subunit RPT5, Human immunodeficiency virus tat transactivator binding protein 1, MGC8487, Proteasome (prosome macropain) 26S subunit ATPase 3, Proteasome 26S ATPase subunit 3, Proteasome 26S subunit ATPase 3, Proteasome subunit P50, PRS6A_HUMAN, PSMC 3, PSMC3, Tat binding protein 1, TAT-binding protein 1, TBP-1, TBP1
背景说明: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.
Swiss Prot: P17980
Gene ID: 5702
亚细胞定位: Cytoplasm Nucleus P-body
免疫原: Recombinant protein of human PSMC3
Public Immunogen Range: 1-180aa
理论分子量: 49kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。