Anti-ABAT Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ABAT Polyclonal Antibody
中文名称： γ氨基丁酸转氨酶抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： IF ; WB
稀释比例： WB 1:500-1000. IF 1:50-200.

抗体信息

靶标： ABAT
别名： ABAT,GABA aminotransferase,GABA AT,GABA T,GABA transaminase,GABAT,L AIBAT
背景说明： 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Swiss Prot： P80404
Gene ID： 18
亚细胞定位： Mitochondrion matrix
免疫原： Recombinant protein of human ABAT
Public Immunogen Range： 29-300aa
理论分子量： 56kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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