Anti-GMNN Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-GMNN Polyclonal Antibody
中文名称： DNA复制抑制因子抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IHC ; WB ; IF
稀释比例： WB 1:500-1000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： GMNN
别名： DNA replication inhibitor, Gem, GEMI_HUMAN, Geminin, Geminin DNA replication inhibitor, GMNN,
背景说明： This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.
Swiss Prot： O75496
Gene ID： 51053
亚细胞定位： Cytoplasm Nucleus
免疫原： Recombinant protein of human GMNN
Public Immunogen Range： 1-209aa
理论分子量： 24kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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