Anti-ATM Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-ATM Polyclonal Antibody
中文名称： 毛细血管扩张性共济失调症突变蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： WB
稀释比例： WB 1:500-1000.

抗体信息

靶标： ATM
别名： AT1;ATA;ATC;ATD;ATDC;ATE;TEL1;TELO1
背景说明： The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
Swiss Prot： Q13315
Gene ID： 472
亚细胞定位： Nucleus Cytoplasm
免疫原： A synthetic peptide of human ATM
Public Immunogen Range： 1900-2000aa
理论分子量： 351kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。