Anti-PFKFB3 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-PFKFB3 Polyclonal Antibody
中文名称： 6-磷酸果糖-2-激酶/果糖-2，6-二磷酸酶3抗体
规格： 50ul ; 100ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应： Mouse ; Human ; Rat
应用： WB ; IHC-P ; ELISA
稀释比例： WB 1:100-500. IHC-P 1:50-200.

抗体信息

靶标： PFKFB3
别名： 6 phosphofructo 2 kinase/ fructose 2,6 bisphosphatase, 6 phosphofructo 2 kinase/fructose 2,6 biphosphatase 3, 6PF 2 K/Fru 2,6 P2ASE brain/placenta type isozyme, 6PF 2-K/Fru 2,6 P2ase 3, fructose 6 phosphate,2 kinase/fructose 2, 6 bisphosphatase, Inducible 6 phosphofructo 2 kinase/fructose 2,6 bisphosphatase, iPFK 2, IPFK2, PFK/FBPase 3, PFK-2, PFK2, Renal carcinoma antigen NY REN 56, uPFK 2, PFKFB3, F263_HUMAN
背景说明： The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q16875
Gene ID： 5209
亚细胞定位： Cytosol Nucleus
研究领域： 新陈代谢 ; 细胞生物学
免疫原： Recombinant protein of human PFKFB3Public Immunogen Range 130-220aa
理论分子量： 60kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.03% Proclin300，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.
运输条件： 冷冻运输

产品介绍 Product Introduction

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