Anti-MDC1 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-MDC1 Polyclonal Antibody
中文名称： DNA损伤关卡蛋白1抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human
应用： IF ; IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:50-200. IF 1:50-200.

抗体信息

靶标： MDC1
别名： NFBD1, Nuclear factor with BRCT domains protein 1, DKFZp781A0122, Homologue to Drosophila photoreceptor protein calphotin, KIAA0170, MGC166888, MDC 1, Mediation of DNA damage checkpoint 1, Mediator of DNA damage checkpoint 1, Mediator of DNA Damage Checkpoint Protein 1, NFBD 1, NFBD1, Nuclear Factor with BRCT Domains Protein 1, MDC1_HUMAN
背景说明： The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
Swiss Prot： Q14676
Gene ID： 9656
亚细胞定位： Chromosome Nucleus
免疫原： Recombinant protein of human MDC1
Public Immunogen Range： 1-350aa
理论分子量： 227/198/117kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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