Anti-NUDT15 Polyclonal Antibody,BR

产品属性 Product Attributes

基本信息

英文名称： Anti-NUDT15 Polyclonal Antibody
中文名称： NUDT15蛋白抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Human ; Mouse ; Rat
应用： IHC ; WB
稀释比例： WB 1:500-2000.IHC 1:50-100

抗体信息

靶标： NUDT15
别名： 8-dihydro-8-oxoguanine triphosphatase NUDT15, 8-oxo-dGTPase NUDT15, A730068G11Rik, EC 3.1.6.-, FLJ10956, MGC104352, MTH2, MutT homolog 2, Nucleoside diphosphate-linked moiety X motif 15, NUD15_HUMAN, Nudix (nucleoside diphosphate linked moiety X)-type motif, Nudix motif 15, NUDT15,
背景说明： This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
Swiss Prot： Q9NV35
Gene ID： 55270
亚细胞定位： Cytosol
免疫原： Recombinant protein of human NUDT15
Public Immunogen Range： 1-164aa
理论分子量： 19kDa

其它标识

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

产品介绍 Product Introduction

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注意事项 Considerations

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