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Anti-PLK3 Polyclonal Antibody,BR
Anti-PLK3 Polyclonal Antibody
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产品属性 Product Attributes
基本信息
英文名称: Anti-PLK3 Polyclonal Antibody规格: 100ul ; 50ul
宿主: Rabbit
克隆类型: Polyclonal Antibody
亚型: IgG
交叉反应:: Mouse ; Rat ; Human
应用: WB
稀释比例: WB 1:500-1000
抗体信息
靶标: PLK3别名: CNK, Cytokine Inducible Kinase, Cytokine-inducible serine/threonine-protein kinase, FGF inducible kinase, FGF-inducible kinase, FNK, PLK-3, Plk3, PLK3_HUMAN, Polo Like Kinase 3, Polo-like kinase 3, PRK, Proliferation Related Kinase, Proliferation-related kinase, Serine/threonine-protein kinase PLK3
背景说明: The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis.
Swiss Prot: Q9H4B4
Gene ID: 1263
亚细胞定位: Cytoplasm Golgi apparatus Nucleus centrosome cytoskeleton microtubule organizing center nucleolus
免疫原: Recombinant protein of human PLK3
Public Immunogen Range: 487-646aa
理论分子量: 72kDa
其它标识
纯化方法: Affinity purification储存液: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存条件: Store at -20℃. Avoid freeze/thaw cycles.
产品介绍 Product Introduction
使用前请离心。如有问题请及时联系我们。Quick spin before use. If you have any questions, please contact us.
注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。
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